Mississippi County, Missouri

Founding: 1845 (declared in 1842)
Parent county: Scott

Namesake: The Mississippi River
Seat: Charleston (1845–)

Land area: 412 square miles

Population (2020): 12,577

Population (historic): 3,123 (1850); 4,982 (1870); 10,134 (1890); 14,557 (1910); 15,762 (1930)

Periods of population growth: pre-1850–1910; 1920–1940; 2000s

Subdivisions: Five cities; two villages; seven townships

National Register listings: 12

Pre-1940 residences (estimated): 653 (11.4%)
Pre-1940 housing survival rate: 13.5%
Pre-1860 housing survival rate (1940): 1.9%

Farm housing in disrepair (1950): 35.2%

Nonfarm housing in disrepair (1950): 36.1%

Average farmhouse value (1930): $562
Average outbuilding value (1930): $411
Number of farms (1920): 1,184
Average farm size (1920): 132 acres
Sources of settlement: Kentucky, Tennessee, and Illinois
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Charleston

Namesake: Uncertain—likely Charleston, South Carolina

Founding: 1837 (platting); 1847 (post office); 1872 (incorporation)

Population (2020): 5,056

Population (historic): 273 (1860); 1,028 (1880); 1,893 (1900); 3,357 (1930)

Periods of population growth: pre-1860–1920; 1930–1960; 1970s; 2000s
Pre-1940 residences (estimated): 308 (14.8%)
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Outstanding Buildings

1. *Jacob Swank House (1839). 260 US Highway 62. Tywappity. Greek Revival.